1-833-ZEPOSIA

ZEPOSIA is a once-daily pill for adults with moderate to severe ulcerative colitis (UC).

Take as directed by your doctor if certain liver problems exist.

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ZEPOSIA is a once-daily pill for adults with moderate to severe ulcerative colitis (UC).

Take as directed by your doctor if certain liver problems exist.

What is ZEPOSIA?

Get to know more about ZEPOSIA, a once-daily pill for UC, the results people saw in clinical studies, and how it could be the right next step for you.

ZEPOSIA® a proven UC treatment icon

Lasting remission

In clinical studies, people taking ZEPOSIA achieved lasting remission (fewer symptoms and reduced inflammation seen during a colonoscopy at 1 year).*

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UC relief without steroids

ZEPOSIA is an advanced once-daily pill you can take without first having to try injections or infusions (biologics)—and it can provide UC relief without having to take steroids.

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Early symptom relief

With ZEPOSIA, you can experience reduced rectal bleeding and fewer trips to the bathroom in as early as 2 weeks.

  • 37% achieved remission vs 19% on placebo. Reduces symptoms of rectal bleeding and stool frequency. Reduced inflammation representing mild or inactive disease in the colon.
  • 32% of patients achieved steroid-free remission at 1 year vs 17% on placebo.
  • Advanced therapies=S1P receptor modulators, biologics, and JAK inhibitors.
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Reduced intestinal inflammation

ZEPOSIA can help with intestinal healing by visibly reducing inflammation on and below the surface of the colon lining.§

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A well-established safety profile across multiple conditions

ZEPOSIA was studied in 4 clinical studies, across 2 conditions.||

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Support and savings

Eligible, commercially insured patients may pay as little as $0 per month for ZEPOSIA with a co-pay savings offer. Additional eligibility requirements and terms & conditions apply. Please click here for more information.

  • 30% of patients achieved this result at 1 year, compared to 14% on placebo. Impact of intestinal healing on UC progression and long-term outcomes was not studied.
  • ZEPOSIA was studied in ulcerative colitis and multiple sclerosis in over 1,300 patients.