1-833-ZEPOSIA
ZEPOSIA is a once-daily pill for adults with moderate to severe ulcerative colitis (UC).
Take as directed by your doctor if certain liver problems exist.
ZEPOSIA is a once-daily pill for adults with moderate to severe ulcerative colitis (UC).
Take as directed by your doctor if certain liver problems exist.
It’s important to know as much as you can when starting a treatment, including its safety information.
The safety of ZEPOSIA has been studied across:
At 10 weeks of treatment, 94% of patients remained on ZEPOSIA in the UC clinical studies, and 3.3% stopped due to a side effect they experienced (N=429).
At 1 year of treatment, 80% of patients remained on ZEPOSIA and 1.3% stopped due to a side effect they experienced (N=230).
ZEPOSIA may cause serious side effects, including:
Contact your healthcare provider right away if you experience the symptoms listed above.
ZEPOSIA may cause serious side effects, including:
The safety of ZEPOSIA was evaluated during a one-year, two-part clinical trial. During the clinical trial, people who took ZEPOSIA (n=429) and those who took placebo (n=216) were asked to report any side effects they experienced. All participants were first evaluated at 10 weeks.
Additional information from another clinical study (which included 67 patients who received ZEPOSIA 0.92 mg once daily) is also included in the first table (below).
Here are the most common side effects reported (in a least 2% of ZEPOSIA participants and ≥1% more than placebo), along with the percentages of people who experienced each.
Side effect (0-9/10 weeks) |
ZEPOSIA 496 patients |
Placebo 281 patients |
---|---|---|
Upper respiratory infection | 5% | 4% |
Elevated liver enzymes | 5% | 0% |
Headache | 4% | 3% |
Fever | 3% | 2% |
Nausea | 3% | 2% |
Joint pain | 3% | 1% |
Participants who achieved symptom relief at 10 weeks were able to continue to the second part of the trial, where they were evaluated again after 1 year (ZEPOSIA: n=230; placebo: n=227).
At 1 year, here were the most common side effects reported (in a least 4% of ZEPOSIA participants and ≥1% more than placebo), along with the percentage of people who experienced each.
Side effect (10-52 weeks) |
ZEPOSIA 230 patients |
Placebo 227 patients |
---|---|---|
Elevated liver enzymes | 11% | 2% |
Headache | 5% | <1% |
If you experience any side effects while taking ZEPOSIA, be sure to talk to your doctor right away. These are not all the possible side effects of ZEPOSIA. To see the full list of side effects, click here.
Since it was first approved, approximately 35,000 patients have received ZEPOSIA across two conditions.*
Please see the full Prescribing Information and Medication Guide for information on all of the side effects reported by those taking ZEPOSIA.