1-833-ZEPOSIA

ZEPOSIA is a once-daily pill for adults with moderate to severe ulcerative colitis (UC).

Take as directed by your doctor if certain liver problems exist.

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ZEPOSIA is a once-daily pill for adults with moderate to severe ulcerative colitis (UC).

Take as directed by your doctor if certain liver problems exist.

4 steps to getting started with ZEPOSIA

There are a few steps to getting started with ZEPOSIA. They will begin once your Start Form (your ZEPOSIA prescription) is submitted.

1 A call from a Support Coordinator
ZEPOSIA® 360 Support - support coordinator icon

If your start form was submitted to the ZEPOSIA 360 Support ProgramTM, a Support Coordinator will call to guide you through the support offerings and financial assistance options available to you. Consider adding this number to your phone so you can identify the call: 1-833-937-6742.

Our Support Coordinators can help with:

Navigating insurance benefits*

  • Depending on your insurance coverage and financial needs, there may be several different ways to save on the cost of ZEPOSIA and the tests needed before treatment. Our Support Coordinators can help you understand your options
  • If you have private or commercial insurance and are experiencing delays or issues with coverage, the ZEPOSIA Bridge Program may be able to provide ZEPOSIA to you, as needed (for up to 24 months). Additional eligibility requirements and terms & conditions apply

Additional financial support options

  • Eligible, commercially insured patients may pay as little as $0 a month for ZEPOSIA. Additional eligibility requirements and terms & conditions apply. Please click here for more information
  • If you have difficulty affording your medication, our Support Coordinators can help you identify options that may be available to you

Additional support team members are also available to answer questions about ZEPOSIA and provide helpful resources.

1-833-ZEPOSIA (1-833-937-6742), Monday to Friday, 8 AM – 8 PM ET.

If you haven’t heard from a Support Coordinator, touch base with your healthcare provider to ensure that your Start Form was submitted to ZEPOSIA 360 Support.

Being enrolled in ZEPOSIA 360 Support helps you access the support you need throughout your entire treatment journey.

  • The accurate completion of reimbursement- or coverage-related documentation is the responsibility of the healthcare provider and patient. Bristol Myers Squibb and its agents make no guarantee regarding reimbursement for any service or item.
  • Additional eligibility requirements and terms and conditions apply. Please see ZEPOSIA Bridge Program Terms and Conditions.
2 Routine tests to get started
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Before you start taking ZEPOSIA, two routine tests are required. If you have a history of certain eye conditions (macular edema or uveitis), or diabetes, you may also need an eye exam. Let your healthcare provider know if you’ve had some of these tests within the last six months—they may not need to be repeated:

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Blood work

Including complete blood count and liver function tests.

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An electrocardiogram (ECG)

A common test that uses small sensors to monitor your heart and makes sure it's working normally before you start treatment.

Tell your UC healthcare provider about all the medications you take, have recently taken, and if you’ve had chickenpox or received the chickenpox vaccine. You may be asked to do a blood test for the chickenpox virus. You may need to get the full course of the vaccine, then wait 1 month before taking ZEPOSIA.

  • These tests can be completed at your home, if you're eligible. ZEPOSIA 360 Support can help schedule them
  • Out-of-pocket costs may be eligible for reimbursement. There may be costs associated with some of the routine medical tests, but depending on where these tests take place, eligible, commercially insured patients may qualify for reimbursement. Additional eligibility requirements and terms & conditions apply. Please click here for more information

The ZEPOSIA Prescribing Information does not require ongoing lab monitoring unless indicated by your healthcare provider.

Trey, real ZEPOSIA® patient
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Once I was prescribed ZEPOSIA, ZEPOSIA 360 Support arranged for a clinician to come to my house to do all the necessary tests.

—Trey
A real ZEPOSIA patient compensated for his time.

See Trey’s story
  • Additional eligibility requirements and terms and conditions apply. Please see ZEPOSIA In-Home Medical Services Program Terms and Conditions.
3 Begin treatment with the Starter Kit
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A gradual start designed with you in mind

Once you’ve been approved to begin treatment, you’ll receive the ZEPOSIA Starter Kit. It will either be provided to you by your healthcare provider or delivered directly to your home. Please see additional eligibility requirements and terms and conditions.§

The ZEPOSIA Starter Kit includes medication for you to begin treatment and has two parts:

ZEPOSIA® 7-day starter pack image
  1. A 7-day Starter Pack for your first week of treatment. The pills in this pack help increase your dosage of ZEPOSIA gradually. Each pill is labeled with the day and dosage. Be sure to follow the instructions written on the pack and take the pills in the correct order
  2. The regular dosage of ZEPOSIA (orange capsules) you’ll begin taking on day 8 (after completing the 7-day Starter Pack)

If you have private or commercial insurance and are experiencing delays or issues with coverage, the ZEPOSIA Bridge Program may be able to provide ZEPOSIA to you for free, as needed, until these issues are resolved (for up to 24 months).

  • Additional eligibility requirements and terms and conditions apply. Please see ZEPOSIA Free Trial Terms and Conditions.
4 Getting ZEPOSIA delivered to you
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You’ll receive a call from your specialty pharmacy A specialty pharmacy is different than a regular retail pharmacy. It distributes medications for certain chronic conditions and delivers them directly to you. Some specialty pharmacies also offer in-store pickup. to confirm the delivery of your ZEPOSIA prescription each month. If you prefer to pick up your prescription in store, simply ask your specialty pharmacy. They may offer that option.

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