About UC
About UC
Understanding how ulcerative colitis (UC) occurs, recognizing common symptoms, and learning how to manage the condition with your healthcare provider can bring you closer to finding the help you need.
This website is intended for U.S. residents 18 years of age or older.
UC is a type of inflammatory bowel
disease (IBD) that causes inflammation
in
the lining of the colon. It is not fully
known what causes UC, but people are
typically diagnosed when they’re in
their 30s using a combination of
symptom
assessment and endoscopy
(ie, colonoscopy).
UC is thought to be related to an irregular immune response. In UC, the immune system responds incorrectly and recruits immune cells to the colon (large intestines and rectum). This results in ongoing (chronic) inflammation that damages the colon and causes the symptoms that people with UC may experience.
UC symptoms can range from mild to severe and can vary depending on the person. Even if you feel fine, flare-ups can be common and unpredictable. Here are some of the most common symptoms:
Answer 7 questions to create a personalized guide to help your UC
healthcare provider better understand your symptoms, their impact, and
ways to address them.
Symptoms (Section 1 of 3)
If selected, select how they've changed
Yes
No
Never
Once
Twice
3 times
or more
Back
Treatment (Section 2 of 3)
Never
Rarely
Often
Always
Back
Lifestyle (Section 3 of 3)
(Select all that apply)
Work/
school
Hobbies
Social
activities
Personal
relationships
Travel
Time with family
Scroll down to review and save
your personalized
discussion
guide. Sharing this information
with
your UC healthcare provider
may help determine
whether your
current approach is right for you.
Since my last appointment,
I have
experienced:
I've experienced weight loss.
In the past year, I've had
flare-ups requiring
steroids
.
I don’t always take my
medication as
regularly as it
has been prescribed.
I feel with the symptom control my current treatment provides.
UC is currently impacting my:
My UC makes me feel:
.
UC is a chronic condition for which treatment is required to help
patients achieve and maintain remission, with the goal of maintaining
a steroid-free remission.
Strategies for management of UC should be determined by the goals of you
and your UC healthcare provider. It is important to discuss your goals as well as understand his or her goals for you.
Keep track of your symptoms and
communicate with your UC healthcare
provider
about how you’re feeling. Regular and open communication can help to
determine the best course of action in managing your UC in a way that works
for you.
Get the information you need
to
learn what makes ZEPOSIA a
different UC treatment.
Sign up for the latest
ZEPOSIA details,
UC tips,
stories from real
people taking
ZEPOSIA,
and more from
ZEPOSIA 360 Support™.
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Do not take ZEPOSIA if you:
Talk to your healthcare provider before taking ZEPOSIA if you have any of these conditions or do not know if you have any of these conditions.
ZEPOSIA may cause serious side effects, including:
Call your healthcare provider right away if you have any of these symptoms of an infection during treatment with ZEPOSIA and for 3 months after your last dose of ZEPOSIA:
Your healthcare provider may delay starting or may stop your ZEPOSIA treatment if you have an infection.
Progressive multifocal leukoencephalopathy (PML). ZEPOSIA can increase your risk for PML, which is a rare brain infection that usually leads to death or severe disability. If PML happens, it usually happens in people with weakened immune systems but has happened in people who do not have weakened immune systems. Symptoms of PML get worse over days to weeks. Call your doctor right away if you have any new or worsening symptoms of PML that have lasted several days, including: weakness on one (1) side of your body, changes in your vision, changes in your thinking or memory, confusion, changes in your personality, loss of coordination in your arms or legs, decreased strength, and/or problems with balance.
Call your healthcare provider if you experience the following symptoms of slow heart rate:
Follow directions from your healthcare provider when starting ZEPOSIA and when you miss a dose.
Continue reading for additional possible serious side effects of ZEPOSIA.
Before taking ZEPOSIA, tell your healthcare provider about all of your medical conditions, including if you:
Tell your healthcare provider about all the medicines you take or have recently taken, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Using ZEPOSIA with other medicines can cause serious side effects. Especially tell your healthcare provider if you take or have taken:
You should not receive live vaccines during treatment with ZEPOSIA, for at least 1 month before taking ZEPOSIA and for 3 months after you stop taking ZEPOSIA. Vaccines may not work as well when given during treatment with ZEPOSIA.
ZEPOSIA can cause serious side effects, including:
The most common side effects of ZEPOSIA can include:
These are not all of the possible side effects of ZEPOSIA. For more information, ask your healthcare provider or pharmacist.
Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 1-800-FDA-1088.
Multiple Sclerosis (MS): ZEPOSIA® (ozanimod) is a prescription medicine used to treat relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.
Ulcerative Colitis (UC): ZEPOSIA is a prescription medicine used to treat moderately to severely active ulcerative colitis (UC) in adults.
It is not known if ZEPOSIA is safe and effective in children.
Please see full Prescribing Information, including Medication Guide.
Do not take ZEPOSIA if you:
Talk to your healthcare provider before taking ZEPOSIA if you have any of these conditions or do not know if you have any of these conditions.
ZEPOSIA may cause serious side effects, including: