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ZEPOSIA is a once-daily pill for adults with relapsing multiple sclerosis (MS).

Take as directed by your doctor if certain liver problems exist.

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ZEPOSIA is a once-daily pill for adults with relapsing multiple sclerosis (MS).

Take as directed by your doctor if certain liver problems exist.

How ZEPOSIA works

MS causes the body’s immune system to malfunction and attack healthy tissue in the central nervous system (CNS). To understand the way ZEPOSIA is thought to work, it’s important to know how a healthy immune system should function and what happens to the immune system in MS.

The immune system is the body’s natural defense system. It’s made up of cells, molecules, tissues, and organs that work together to protect the body.

In people without MS, disease-fighting immune cells circulate in the bloodstream, some of them passing through small glands called lymph nodes and traveling throughout the body to wherever they are needed.

These immune cells are not meant to enter the brain or any other part of the CNS.

Immune system (person without MS) illustration Immune system (person without MS) illustration

For illustrative purposes only.

In people with MS, the immune system malfunctions. When the immune system malfunctions, the immune cells move through the lymph nodes into the brain and other parts of the CNS.

In the CNS, these immune cells attack healthy tissue, incorrectly assuming that it’s a foreign substance—and damaging it.

When the tissue is damaged, it causes problems in the CNS. When the CNS isn’t functioning properly it can lead to issues that are typically related to MS. You can Learn more about MS here.

Immune cells in lymph nodes (person with MS) illustration Immune cells in lymph nodes (person with MS) illustration

For illustrative purposes only.

The way ZEPOSIA works is not known. However, it is thought that ZEPOSIA acts as a gatekeeper, by keeping immune cells from moving out of the lymph nodes and into the CNS, which may prevent damage to the CNS.

ZEPOSIA® is thought to act as gatekeeper illustration ZEPOSIA® is thought to act as gatekeeper illustration

For illustrative purposes only.

2084-US-2400429 07/24