Getting started
with ZEPOSIA
ZEPOSIA is for adults.
These steps will begin once your Start Form (your ZEPOSIA prescription) is submitted to ZEPOSIA 360 Support™.
Step
1
As your dedicated point of contact for all things ZEPOSIA, your
MS Nurse Navigator will call you to get things started.
Consider adding this number to your phone so you can identify the call:
They can help in a number of ways, including:
If you haven’t heard from your Nurse Navigator, reach out to your healthcare team to ensure that your Start Form was submitted to ZEPOSIA 360 Support.
This type of insurance is usually provided by an employer or a union, or purchased directly from an insurance company.
Step
2
Before you start taking ZEPOSIA, two routine tests are required. If you have a history of certain eye conditions (macular edema or uveitis) you may also need an eye exam. Let your healthcare team know if you’ve had some of these tests within the last six months—they may not need to be repeated:
Blood work—including complete blood count and liver function test.
These tests can be completed at your home, if you’re eligible.§ Your MS Nurse Navigator can help schedule them
Any potential out-of-pocket costs may be reimbursed. There may be costs associated with some of the routine medical tests, but depending on where these tests take place, eligible patients may qualify for reimbursement or incur no costs at all†
Step
3
A specialty pharmacy is different than a regular retail pharmacy. It distributes medications for certain chronic conditions and delivers them directly to you. Some specialty pharmacies also offer
The ZEPOSIA Starter Kit includes medication for the first 37 days of treatment and has two parts:
ZEPOSIA will be delivered to you going forward You'll receive a call to confirm the delivery of your ZEPOSIA prescription each month. If you prefer to pick up your prescription in store, you can ask your specialty pharmacy if they offer that option.
Eligible patients can receive a
||Program terms and eligibility criteria apply.
*To receive a free Bridge Supply of ZEPOSIA, you must have an on‐label diagnosis and be denied or experiencing a delay in obtaining coverage under your private or commercial insurance for ZEPOSIA. Federal, state, or similar insurance plans are not eligible for Bridge. Once ZEPOSIA is approved by your commercial insurance plan, you will no longer be eligible for the Bridge Program. The Bridge Program is available where not otherwise prohibited by state or local law.
†Depending on insurance coverage and where the full cost is not covered by patients’ insurance, eligible patients may receive a prescription benefit offer for out-of-pocket drug costs and pay as little as $0 per prescription, as well as a medical assessment benefit offer for out-of-pocket costs for the initial blood tests, ECG screening, and eye exam. Maximum savings limit applies; patient out-of-pocket expenses may vary. This program is not health insurance. Offer not valid for patients enrolled in Medicare, Medicaid, or other federal or state healthcare programs. Click here for Program Terms, Conditions, and Eligibility Criteria.
‡Data provided by Bristol Myers Squibb and is current as of September 2021.
§Home visits for routine medical tests are not available to people enrolled in Medicare, Medicaid, or other federal or state healthcare programs, or to people living in Rhode Island.
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Do not take ZEPOSIA if you:
Talk to your healthcare provider before taking ZEPOSIA if you have any of these conditions or do not know if you have any of these conditions.
ZEPOSIA may cause serious side effects, including:
Call your healthcare provider right away if you have any of these symptoms of an infection during treatment with ZEPOSIA and for 3 months after your last dose of ZEPOSIA:
Your healthcare provider may delay starting or may stop your ZEPOSIA treatment if you have an infection.
Progressive multifocal leukoencephalopathy (PML). ZEPOSIA can increase your risk for PML, which is a rare brain infection that usually leads to death or severe disability. If PML happens, it usually happens in people with weakened immune systems but has happened in people who do not have weakened immune systems. Symptoms of PML get worse over days to weeks. Call your doctor right away if you have any new or worsening symptoms of PML that have lasted several days, including: weakness on one (1) side of your body, changes in your vision, changes in your thinking or memory, confusion, changes in your personality, loss of coordination in your arms or legs, decreased strength, and/or problems with balance.
Call your healthcare provider if you experience the following symptoms of slow heart rate:
Follow directions from your healthcare provider when starting ZEPOSIA and when you miss a dose.
Continue reading for additional possible serious side effects of ZEPOSIA.
Before taking ZEPOSIA, tell your healthcare provider about all of your medical conditions, including if you:
Tell your healthcare provider about all the medicines you take or have recently taken, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Using ZEPOSIA with other medicines can cause serious side effects. Especially tell your healthcare provider if you take or have taken:
You should not receive live vaccines during treatment with ZEPOSIA, for at least 1 month before taking ZEPOSIA and for 3 months after you stop taking ZEPOSIA. Vaccines may not work as well when given during treatment with ZEPOSIA.
ZEPOSIA can cause serious side effects, including:
The most common side effects of ZEPOSIA can include:
These are not all of the possible side effects of ZEPOSIA. For more information, ask your healthcare provider or pharmacist.
Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Multiple Sclerosis (MS): ZEPOSIA® (ozanimod) is a prescription medicine used to treat relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.
Ulcerative Colitis (UC): ZEPOSIA is a prescription medicine used to treat moderately to severely active ulcerative colitis (UC) in adults.
It is not known if ZEPOSIA is safe and effective in children.
Please see full Prescribing Information, including Medication Guide.
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Do not take ZEPOSIA if you: